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1.
Lab Chip ; 22(17): 3245-3257, 2022 08 23.
Artículo en Inglés | MEDLINE | ID: mdl-35899760

RESUMEN

Inertial migration of deformable particles has become appealing in recent years due to its numerous applications in microfluidics and biomedicine. The physics underlying the motion of these particles is contingent upon the presence of lift forces in microchannels. Therefore, in this work, we present a lift force analysis for such migration of a deformable droplet in steady and oscillatory flow regimes and identify the effects of varying Capillary number and oscillation frequency on its dynamics. We then propose an expression that mimics the lift force behavior in oscillatory flows accurately. Finally, we introduce a procedure to derive and predict a simple expression for the steady and averaged oscillatory lift for any given combination of Capillary number and oscillation frequency within a continuous range.


Asunto(s)
Técnicas Analíticas Microfluídicas , Técnicas Analíticas Microfluídicas/métodos , Microfluídica , Movimiento (Física) , Tamaño de la Partícula
2.
Int J Oral Maxillofac Implants ; 37(2): 302-310, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35476858

RESUMEN

PURPOSE: The aim of this study was to evaluate and compare the effect of changing five macrostructural design parameters of dental implants on the peak strains experienced by the interfacial bone. MATERIALS AND METHODS: Five geometric variables, including three body-related (implant length, diameter, and taper) and two thread-related (thread depth and thread angle) parameters, were defined. The alveolar bone was modeled as a block with anisotropic and linearly elastic properties with 20-mm height and 12-mm buccolingual and mesiodistal dimensions. Oblique occlusal loads (100-N vertical and 20-N horizontal) were applied to the abutment surface. A total of 162 models with different designs were defined by implementation of a full-factorial design. The peak values of the compressive and tensile principal strains in the cortical and cancellous bones were calculated by finite element analysis (FEA). RESULTS: Implant diameter and length had maximum and minimum effects on the peak compressive and tensile strains at the cortical interface, respectively. Implant diameter and thread depth had maximum and minimum effects on the maximum compressive strain at the cancellous interface, while thread angle and length had maximum and minimum significant effects on the maximum tensile strain at the cancellous interface. CONCLUSION: The interaction of thread parameters and taper has the greatest effect on the peak compressive and tensile strains at the cancellous interface and also on the peak tensile strain at the cortical interface, while body-related parameters are more effective on the peak compressive strain at the cortical interface.


Asunto(s)
Implantes Dentales , Simulación por Computador , Diseño de Prótesis Dental , Análisis de Elementos Finitos
3.
Sci Rep ; 11(1): 21675, 2021 11 04.
Artículo en Inglés | MEDLINE | ID: mdl-34737389

RESUMEN

The recent outbreak of the COVID-19 led to death of millions of people worldwide. To stave off the spread of the virus, the authorities in the US employed different strategies, including the mask mandate order issued by the states' governors. In the current work, we defined a parameter called average death ratio as the monthly average of the number of daily deaths to the monthly average number of daily cases. We utilized survey data to quantify people's abidance by the mask mandate order. Additionally, we implicitly addressed the extent to which people abide by the mask mandate order, which may depend on some parameters such as population, income, and education level. Using different machine learning classification algorithms, we investigated how the decrease or increase in death ratio for the counties in the US West Coast correlates with the input parameters. The results showed that for the majority of counties, the mask mandate order decreased the death ratio, reflecting the effectiveness of such a preventive measure on the West Coast. Additionally, the changes in the death ratio demonstrated a noticeable correlation with the socio-economic condition of each county. Moreover, the results showed a promising classification accuracy score as high as 90%.


Asunto(s)
COVID-19/mortalidad , COVID-19/prevención & control , Máscaras/tendencias , California , Adhesión a Directriz/tendencias , Política de Salud , Humanos , Aprendizaje Automático , Máscaras/estadística & datos numéricos , Oregon , SARS-CoV-2/patogenicidad , Washingtón
4.
Phys Rev E ; 102(6-1): 063110, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33466115

RESUMEN

Dynamics of a deformable capsule in an oscillatory flow of a Newtonian fluid in a microchannel has been studied numerically. The effects of oscillation frequency, capsule deformability, and channel flow rate have been explored by simulating the capsule within a microchannel. In addition, the simulation captures the effect of the type of imposed pressure oscillations on the migration pattern of the capsule. An oscillatory channel flow enables the focusing of extremely small biological particles by eliminating the need to design impractically long channels. The presented results show that the equilibrium position of the capsule changes not only by the addition of an oscillatory component to the pressure gradient but it also is influenced by the capsule deformability and channel flow rate. Furthermore, it has been shown that the amplitude of oscillation of capsules decreases as the channel flow rate and the rigidity of the capsule increases.

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